hb

The gene hunchback is referred to in FlyBase by the symbol Dmelhb (CG9786, FBgn0001180). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 3R:8690980..8697822. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity. It is involved in the biological process described with 15 unique terms, many of which group under: posterior head segmentation; regulation of neural precursor cell proliferation; regulation of development, heterochronic; gland development; zygotic determination of anterior/posterior axis, embryo. 140 alleles are reported. The phenotypes of these alleles manifest in: peripheral nervous system; primordial germ cell; spiracular chamber; trichome field; embryonic/larval midgut. The phenotypic classes of alleles include: phenotype; embryonic/larval segmentation phenotype; increased mortality; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages.

hunchback

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6