kn

The gene knot is referred to in FlyBase by the symbol Dmelkn (CG10197, FBgn0001319). It is a protein_coding_gene from Dmel. It has 5 annotated transcripts and 5 polypeptides (all unique). Gene sequence location is 2R:14772650..14807061. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein dimerization activity. It is involved in the biological process described with 22 unique terms, many of which group under: regulation of plasma membrane bounded cell projection organization; cell communication; response to symbiont; post-embryonic animal organ morphogenesis; regulation of multicellular organismal development. 51 alleles are reported. The phenotypes of these alleles manifest in: larval metathoracic segment; embryonic/larval foregut; embryonic/larval hemocyte; dorsal closure embryo; neuroblast NB5-6 of abdomen. The phenotypic classes of alleles include: increased mortality; sensory perception defective; immune response defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed at stages throughout embryogenesis.

knot

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6