msl-2

Information msl-2

Description

The gene male-specific lethal 2 is referred to in FlyBase by the symbol Dmelmsl-2 (CG3241, FBgn0005616). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:3462218..3466112. Its molecular function is described by: chromatin binding; DNA binding; ubiquitin protein ligase activity; transcription factor binding. It is involved in the biological process described with 7 unique terms, many of which group under: macromolecule metabolic process; protein metabolic process; dosage compensation by hyperactivation of X chromosome; gene expression; regulation of metabolic process. 84 alleles are reported. The phenotype of these alleles manifest in: eye. The phenotypic classes of alleles include: partially lethal; phenotype; increased mortality during development; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages.

Full Name

male-specific lethal 2

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
21
Biotypes
3
Peaks
137,629
Non-redundant peaks
59,710

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
33565
Official Gene Name
msl-2
JASPAR
Ensembl
FBgn0005616
UniProt
P50534
Genevisible
P50534
RefSeq
NM_164536
Aliases
msl-2
All peaks msl-2
Download BED file
Non redundant peaks msl-2
Download BED file
SEQUENCES msl-2
Download FASTA file
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Datasets Table for msl-2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
msl-2 Schneider-2 gst_RNAi3 GEO Drosophila melanogaster GSE119708 3,211
msl-2 Schneider-2 gst_RNAi2 GEO Drosophila melanogaster GSE119708 2,155
msl-2 Schneider-2 Trl_RNAi2 GEO Drosophila melanogaster GSE119708 1,962
msl-2 Schneider-2 Trl_RNAi3 GEO Drosophila melanogaster GSE119708 1,906
msl-2 Schneider-2 Clamp1_RNAi1 GEO Drosophila melanogaster GSE119708 3,462
msl-2 Schneider-2 GEO Drosophila melanogaster GSE94115 7,332
msl-2 Schneider-2 Clamp1_RNAi3 GEO Drosophila melanogaster GSE119708 4,752
msl-2 Schneider-2 Clamp2_RNAi2 GEO Drosophila melanogaster GSE119708 597
msl-2 Schneider-2 gst_RNAi1 GEO Drosophila melanogaster GSE119708 4,917
msl-2 Schneider-2 Clamp2_RNAi3 GEO Drosophila melanogaster GSE119708 2,576
msl-2 Schneider-2 Trl_RNAi1 GEO Drosophila melanogaster GSE119708 5,314
msl-2 Kc sxl1_3d GEO Drosophila melanogaster GSE75031 1,096
msl-2 Kc sxl1_9d GEO Drosophila melanogaster GSE75031 2,000
msl-2 Kc sxl2_3d GEO Drosophila melanogaster GSE75031 4,592
msl-2 Kc sxl2_6d GEO Drosophila melanogaster GSE75031 5,249
msl-2 Kc sxl2_9d GEO Drosophila melanogaster GSE75031 6,729
msl-2 Kc sxl1_6d GEO Drosophila melanogaster GSE75031 5,731
msl-2 Kc gfp_3d GEO Drosophila melanogaster GSE75031 1,790
msl-2 third-instar male GEO Drosophila melanogaster GSE129795 37,929
msl-2 third-instar white-eyed_male GEO Drosophila melanogaster GSE109898 21,805
msl-2 third-instar white-eyed_female GEO Drosophila melanogaster GSE109898 12,524
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks