p53

The gene p53 is referred to in FlyBase by the symbol Dmelp53 (CG33336, FBgn0039044). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (3 unique). Gene sequence location is 3R:23049657..23054082. Its molecular function is described by 10 unique terms, many of which group under: binding; protein binding; nucleic acid binding; transcription regulatory region sequence-specific DNA binding; transcription factor binding. It is involved in the biological process described with 40 unique terms, many of which group under: response to abiotic stimulus; cellular response to radiation; response to gamma radiation; regulation of photoreceptor cell differentiation; regulation of peptide transport. 78 alleles are reported. The phenotypes of these alleles manifest in: adult circulatory system; secondary lysosome; primordial germ cell; supramolecular complex; adult fat body. The phenotypic classes of alleles include: lethal; phenotype; increased mortality during development; cell death defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

p53

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6