pb

Information pb

Description

The gene proboscipedia is referred to in FlyBase by the symbol Dmelpb (CG31481, FBgn0051481). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (all unique). Gene sequence location is 3R:6707800..6742063. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: proboscis development; regulation of transcription by RNA polymerase II; specification of segmental identity, labial segment; specification of segmental identity, maxillary segment. 98 alleles are reported. The phenotypes of these alleles manifest in: anterior endoderm derivative; ganglion; head capsule; mesothoracic leg; embryonic procephalic segment. The phenotypic classes of alleles include: lethal; some die during pupal stage; visible; short lived; lethal - all die before end of pupal stage; wild-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.

Full Name

proboscipedia

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
3
Biotypes
2
Peaks
51,497
Non-redundant peaks
41,277

TF Classification

Familly
Homeo domain factors
Sub Familly
HOX-related factors

Source JASPAR

External IDs

NCBI Gene
40826
Official Gene Name
pb
JASPAR
MA0238.1
Ensembl
FBgn0051481
UniProt
P31264
Genevisible
P31264
RefSeq
NM_206441
Aliases
pb
All peaks pb
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Non redundant peaks pb
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SEQUENCES pb
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Datasets Table for pb

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
pb adult whole-fly_site-specific-recombination_insertion ENCODE Drosophila melanogaster ENCSR946EAE 35,310
pb Kc167 Hth GEO Drosophila melanogaster GSE122574 8,198
pb Kc167 GEO Drosophila melanogaster GSE122574 7,989
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks