twi

The gene twist is referred to in FlyBase by the symbol Dmel wi (CG2956, FBgn0003900). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (1 unique). Gene sequence location is 2R:22985374..23048325. Its molecular function is described by: DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein heterodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein homodimerization activity. It is involved in the biological process described with 16 unique terms, many of which group under: regulation of biological process; cell-cell signaling; cellular component organization or biogenesis; Malpighian tubule morphogenesis; regulation of cellular process. 47 alleles are reported. The phenotypes of these alleles manifest in: embryonic/larval muscle system; presumptive embryonic/larval digestive system; midgut primordium; endodermal derivative; foregut. The phenotypic classes of alleles include: increased mortality; increased mortality during development; lethal - all die before end of pupal stage; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

twist

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6