islet
Information for islet
- Description
Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus.
- Source BRENDA Tissue Ontology (BTO)
ReMap Statistics
- Datasets
- 5
- Transcriptional Factors
- 4
- Peaks
- 279,125
- Non-redundant peaks
- 248,888
Description
- Cell_name
- pancreatic islet
External IDs
- Cellosaurus
- Experimental Factor
- BRENDA Tissue
- BTO:0000991
- Wiki
- islet
- ATCC
- islet
- Synonyms
- island of Langerhans; island of pancreas; islet of Langerhans
Datasets Table for islet
Biotype | Biotype modification | Ecotype | Target name | Target modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
islet | CTCF | GEO | Homo sapiens | GSE23784 | Download (35824) | |||
islet | MAFB | ENA | Homo sapiens | ERP004003 | Download (53286) | |||
islet | CTCF | ENA | Homo sapiens | ERP004003 | Download (63251) | |||
islet | NKX3-1 | ENA | Homo sapiens | ERP004003 | Download (71862) | |||
islet | PDX1 | ENA | Homo sapiens | ERP001456 | Download (54902) | |||
Biotype | Biotype modification | Ecotype | Target name | Target modification | Source | Species | Experiment | Peaks |