macrophage

Information for macrophage

Description

Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kupffer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans giant cells.

Source BRENDA Tissue Ontology (BTO)

ReMap Statistics

Datasets
96
Transcriptional Factors
23
Peaks
3,117,776
Non-redundant peaks
1,332,956

Description

Cell_name
macrophage

External IDs

Cellosaurus
macrophagocyte
Experimental Factor
BRENDA Tissue
BTO_0000801
Wiki
macrophage
ATCC
macrophage
Synonyms
All peaks macrophage
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Non redundant macrophage
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CRMs macrophage
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Datasets Table for macrophage

BiotypeBiotype modificationEcotypeTarget nameTarget modificationSourceSpeciesExperimentPeaks
macrophage hybrid SPI1 GEO Mus musculus GSE46494 Download (56522)
macrophage veh CEBPA GEO Mus musculus GSE111854 Download (7409)
macrophage NR1D2 GEO Mus musculus GSE45914 Download (25747)
macrophage B6_Kdo2-LipidA RELA GEO Mus musculus GSE46494 Download (77743)
macrophage KLA-1h_BL6 JUND GEO Mus musculus GSE111854 Download (48578)
macrophage LPM_DMSO SPI1 GEO Mus musculus GSE62826 Download (11858)
macrophage veh_BL6 JUND GEO Mus musculus GSE111854 Download (21937)
macrophage NFE2L2 GEO Mus musculus GSE75175 Download (21539)
macrophage IL10 STAT3 GEO Mus musculus GSE31529 Download (130)
macrophage Pparg-KO ATF3 GEO Mus musculus GSE111854 Download (56491)
BiotypeBiotype modificationEcotypeTarget nameTarget modificationSourceSpeciesExperimentPeaks
Showing 1 to 10 of 96 entries