AFF4

Information AFF4

Description

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]

Full Name

AF4/FMR2 family member 4

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
11
Biotypes
5
Peaks
230,337
Non-redundant peaks
108,569

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
27125
Official Gene Name
AFF4
JASPAR
Ensembl
ENSG00000072364
UniProt
Q9UHB7
Genevisible
Q9UHB7
RefSeq
NM_014423
Aliases
AF5Q31; CHOPS; MCEF
All peaks AFF4
Download BED file
Non redundant peaks AFF4
Download BED file
SEQUENCES AFF4
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for AFF4

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
AFF4 MCF-7 GEO Homo sapiens GSE144036 20,327
AFF4 HEK293T GEO Homo sapiens GSE34097 266
AFF4 HeLa DOX GEO Homo sapiens GSE40632 48,103
AFF4 HeLa EGF GEO Homo sapiens GSE40632 42,203
AFF4 HeLa GEO Homo sapiens GSE40632 40,296
AFF4 HeLa DOX_EGF GEO Homo sapiens GSE40632 46,060
AFF4 CD4 Th1_DMSO GEO Homo sapiens GSE62482 18,454
AFF4 CD4 Th1_BAY GEO Homo sapiens GSE62482 11,253
AFF4 HCT-116 STARVED GEO Homo sapiens GSE30267 391
AFF4 HCT-116 SERUM GEO Homo sapiens GSE30267 1,097
AFF4 HCT-116 GEO Homo sapiens GSE47938 1,887
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks