AFF4
Information AFF4
- Description
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]
- Full Name
AF4/FMR2 family member 4
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 11
- Biotypes
- 5
- Peaks
- 230,337
- Non-redundant peaks
- 108,569
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for AFF4
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| AFF4 | MCF-7 | GEO | Homo sapiens | GSE144036 | 20,327 | |||
| AFF4 | HEK293T | GEO | Homo sapiens | GSE34097 | 266 | |||
| AFF4 | HeLa | DOX | GEO | Homo sapiens | GSE40632 | 48,103 | ||
| AFF4 | HeLa | EGF | GEO | Homo sapiens | GSE40632 | 42,203 | ||
| AFF4 | HeLa | GEO | Homo sapiens | GSE40632 | 40,296 | |||
| AFF4 | HeLa | DOX_EGF | GEO | Homo sapiens | GSE40632 | 46,060 | ||
| AFF4 | CD4 | Th1_DMSO | GEO | Homo sapiens | GSE62482 | 18,454 | ||
| AFF4 | CD4 | Th1_BAY | GEO | Homo sapiens | GSE62482 | 11,253 | ||
| AFF4 | HCT-116 | STARVED | GEO | Homo sapiens | GSE30267 | 391 | ||
| AFF4 | HCT-116 | SERUM | GEO | Homo sapiens | GSE30267 | 1,097 | ||
| AFF4 | HCT-116 | GEO | Homo sapiens | GSE47938 | 1,887 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |