ARID1A
Information ARID1A
- Description
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Full Name
AT-rich interaction domain 1A
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 17
- Biotypes
- 9
- Peaks
- 608,541
- Non-redundant peaks
- 270,799
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for ARID1A
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
ARID1A | MCF-7 | GEO | Homo sapiens | GSE123284 | 34,276 | |||
ARID1A | MCF-7 | Fulvestrant | GEO | Homo sapiens | GSE123284 | 47,038 | ||
ARID1A | MCF-7 | JQ1 | GEO | Homo sapiens | GSE123284 | 33,731 | ||
ARID1A | HAP1 | GEO | Homo sapiens | GSE108387 | 24,967 | |||
ARID1A | MCF-7 | 4-hydroxytamoxifen | GEO | Homo sapiens | GSE123284 | 71,527 | ||
ARID1A | 12Z | GEO | Homo sapiens | GSE129781 | 79,597 | |||
ARID1A | NGP | GEO | Homo sapiens | GSE134626 | 31,292 | |||
ARID1A | Hep-G2 | GEO | Homo sapiens | GSE69566 | 16,502 | |||
ARID1A | LNCaP | r1881 | GEO | Homo sapiens | GSE94682 | 28,264 | ||
ARID1A | LNCaP | GEO | Homo sapiens | GSE94682 | 13,287 | |||
ARID1A | MCF-7 | estrogen | GEO | Homo sapiens | GSE123284 | 16,624 | ||
ARID1A | MCF-7 | DCDT | GEO | Homo sapiens | GSE123284 | 36,460 | ||
ARID1A | H9 | GEO | Homo sapiens | GSE139260 | 7,757 | |||
ARID1A | RMG-I | GEO | Homo sapiens | GSE120058 | 30,122 | |||
ARID1A | RMG-I | GEO | Homo sapiens | GSE104545 | 45,278 | |||
ARID1A | endometrial-epithelial-cells | KO | GEO | Homo sapiens | GSE106660 | 33,814 | ||
ARID1A | endometrial-epithelial-cells | GEO | Homo sapiens | GSE106660 | 58,005 | |||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |