Atf3

The gene Activating transcription factor 3 is referred to in FlyBase by the symbol DmelAtf3 (CG11405, FBgn0028550). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is X:1242740..1275284. Its molecular function is described by: protein binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: nervous system development; regulation of lipid storage; lipid homeostasis; regulation of transcription by RNA polymerase II; immune response. 27 alleles are reported. The phenotypes of these alleles manifest in: lipid droplet; embryonic/larval fat body; adult cuticle; adult abdomen; eye. The phenotypic classes of alleles include: phenotype; increased mortality; increased mortality during development; lethal - all die before end of P-stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages.

Activating transcription factor 3

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6