BACH2
Information BACH2
- Description
Transcriptional regulator that acts as repressor or activator (PubMed:8887638). Binds to Maf recognition elements (MARE) (PubMed:8887638). Plays an important role in coordinating transcription activation and repression by MAFK (PubMed:8887638). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (By similarity). Positively regulates the nuclear import of actin (PubMed:26021350). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation (PubMed:28530713). {ECO:0000250|UniProtKB:Q9BYV9, ECO:0000269|PubMed:26021350, ECO:0000269|PubMed:28530713}.(Source UnitProtKB).
- Full Name
BTB and CNC homology, basic leucine zipper transcription factor 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 126,979
- Non-redundant peaks
- 92,965
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 12014
- Official Gene Name
- Bach2
- JASPAR
- MGI
- MGI:894679
- Ensembl
- ENSMUSG00000040270
- UniProt
- P97303
- Genevisible
- P97303
- RefSeq
- NM_001109661
- Aliases
- E030004N02Rik
Datasets Table for BACH2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| BACH2 | spleen | GEO | Mus musculus | GSE45975 | 22,705 | |||
| BACH2 | CD4 | GEO | Mus musculus | GSE63380 | 16,675 | |||
| BACH2 | M1 | GEO | Mus musculus | GSE79138 | 865 | |||
| BACH2 | pre-pro-B-cell | GEO | Mus musculus | GSE87503 | 63,451 | |||
| BACH2 | CD4 | KO | GEO | Mus musculus | GSE63380 | 16,140 | ||
| BACH2 | spleen | GEO | Mus musculus | GSE126800 | 7,143 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |