BATF3
Information BATF3
- Description
AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. {ECO:0000269|PubMed:19008445, ECO:0000269|PubMed:20351058, ECO:0000269|PubMed:21867928}.(Source UnitProtKB).
- Full Name
basic leucine zipper transcription factor, ATF-like 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 71,706
- Non-redundant peaks
- 40,902
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 381319
- Official Gene Name
- Batf3
- JASPAR
- MGI
- MGI:1925491
- Ensembl
- ENSMUSG00000026630
- UniProt
- Q9D275
- Genevisible
- Q9D275
- RefSeq
- NM_030060
- Aliases
- 9130211I03Rik
Datasets Table for BATF3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| BATF3 | Th2 | GEO | Mus musculus | GSE85172 | 28,227 | |||
| BATF3 | dendritic-cell | CD24 | GEO | Mus musculus | GSE66899 | 15,252 | ||
| BATF3 | Th2 | BATF-KO | GEO | Mus musculus | GSE85172 | 28,227 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |