BHLHA15
Information BHLHA15
- Description
Plays a role in controlling the transcriptional activity of MyoD, ensuring that expanding myoblast populations remain undifferentiated (PubMed:17612490). Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. {ECO:0000269|PubMed:15003629, ECO:0000269|PubMed:15665001, ECO:0000269|PubMed:17612490, ECO:0000269|PubMed:9482738}.(Source UnitProtKB).
- Full Name
basic helix-loop-helix family, member a15
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 51,444
- Non-redundant peaks
- 50,395
TF Classification
- Familly
- Basic helix-loop-helix factors (bHLH)
- Sub Familly
- Tal-related factors
Source JASPAR
External IDs
- NCBI Gene
- 17341
- Official Gene Name
- Bhlha15
- JASPAR
- MA0607.1
- MGI
- MGI:891976
- Ensembl
- ENSMUSG00000052271
- UniProt
- Q9QYC3
- Genevisible
- Q9QYC3
- RefSeq
- NM_010800
- Aliases
- 1810009C13Rik; Bhlhb8; MIST-1; Mist1
Datasets Table for BHLHA15
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| BHLHA15 | fibroblast | GEO | Mus musculus | GSE119782 | 3,333 | |||
| BHLHA15 | pancreas | K1 | GEO | Mus musculus | GSE86289 | 48,111 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |