BMPR1A

Information BMPR1A

Description

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]

Full Name

bone morphogenetic protein receptor type 1A

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
30,442
Non-redundant peaks
30,442

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
657
Official Gene Name
BMPR1A
JASPAR
Ensembl
ENSG00000107779
UniProt
P36894
Genevisible
P36894
RefSeq
NM_004329
Aliases
10q23del; ACVRLK3; ALK3; CD292; SKR5
All peaks BMPR1A
Download BED file
Non redundant peaks BMPR1A
Download BED file
SEQUENCES BMPR1A
Download FASTA file
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Datasets Table for BMPR1A

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
BMPR1A HUVEC-C GEO Homo sapiens GSE60156 30,442
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks