BuGZ

The gene Bub3 interacting GLEBS and Zinc finger domain protein is referred to in FlyBase by the symbol DmelBuGZ (CG17912, FBgn0032600). It is a protein_coding_gene from Dmel. It has 7 annotated transcripts and 7 polypeptides (5 unique). Gene sequence location is 2L:16743405..16753704. Its molecular function is described by: DNA binding; microtubule binding. It is involved in the biological process described with: mitotic spindle assembly checkpoint; attachment of spindle microtubules to kinetochore; mitotic spindle assembly; dendrite morphogenesis. 10 alleles are reported. The phenotypes of these alleles manifest in: myofibril; larval ventral multidendritic neuron vdaB; sarcomere; indirect flight muscle. The phenotypic classes of alleles include: viable; partially lethal - majority die; some die during pupal stage; flightless; neuroanatomy defective. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Bub3 interacting GLEBS and Zinc finger domain protein

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6