CBX1

Information CBX1

Description

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Full Name

chromobox 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
118,743
Non-redundant peaks
107,179

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
10951
Official Gene Name
CBX1
JASPAR
Ensembl
ENSG00000108468
UniProt
P83916
Genevisible
P83916
RefSeq
NM_001127228
Aliases
CBX; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta
All peaks CBX1
Download BED file
Non redundant peaks CBX1
Download BED file
SEQUENCES CBX1
Download FASTA file
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Datasets Table for CBX1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CBX1 K-562 ENCODE Homo sapiens ENCSR948QLZ 33,172
CBX1 Hep-G2 ENCODE Homo sapiens ENCSR819WZE 68,950
CBX1 DKO GEO Homo sapiens GSE135580 16,120
CBX1 HCT-116 GEO Homo sapiens GSE135580 501
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks