CBX3

Information CBX3

Description

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

Full Name

chromobox 3

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
3
Peaks
29,717
Non-redundant peaks
29,529

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
11335
Official Gene Name
CBX3
JASPAR
Ensembl
ENSG00000122565
UniProt
Q13185
Genevisible
Q13185
RefSeq
NM_007276
Aliases
HECH; HP1-GAMMA; HP1Hs-gamma
All peaks CBX3
Download BED file
Non redundant peaks CBX3
Download BED file
SEQUENCES CBX3
Download FASTA file
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Datasets Table for CBX3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CBX3 K-562 ENCODE Homo sapiens ENCSR000ATV 296
CBX3 T-47D-MTVL BPTF GEO Homo sapiens GSE64467 370
CBX3 T-47D-MTVL GEO Homo sapiens GSE64467 1,306
CBX3 HCT-116 ENCODE Homo sapiens ENCSR000BUH 27,745
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks