CBX5
Information CBX5
- Description
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity). {ECO:0000250|UniProtKB:P45973}.(Source UnitProtKB).
- Full Name
chromobox 5
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 9,708
- Non-redundant peaks
- 9,708
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 12419
- Official Gene Name
- Cbx5
- JASPAR
- MGI
- MGI:109372
- Ensembl
- ENSMUSG00000009575
- UniProt
- Q61686
- Genevisible
- Q61686
- RefSeq
- NM_007626
- Aliases
- 2610029O15Rik; C75991; HP1; HP1a; Hp1a; Hp1alpha; heterochromatin protein 1 alpha