CBX5

Information CBX5

Description

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Full Name

chromobox 5

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
32,281
Non-redundant peaks
29,962

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
23468
Official Gene Name
CBX5
JASPAR
Ensembl
ENSG00000094916
UniProt
P45973
Genevisible
P45973
RefSeq
NM_001127321
Aliases
HEL25; HP1; HP1-ALPHA; HP1A; HP1Hs-alpha
All peaks CBX5
Download BED file
Non redundant peaks CBX5
Download BED file
SEQUENCES CBX5
Download FASTA file
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Datasets Table for CBX5

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CBX5 K-562 ENCODE Homo sapiens ENCSR272JAT 9,503
CBX5 GM12878 ENCODE Homo sapiens ENCSR372GIN 12,736
CBX5 DKO GEO Homo sapiens GSE135580 618
CBX5 HCT-116 GEO Homo sapiens GSE135580 9,424
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks