CBX5
Information CBX5
- Description
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Full Name
chromobox 5
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 32,281
- Non-redundant peaks
- 29,962
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 23468
- Official Gene Name
- CBX5
- JASPAR
- Ensembl
- ENSG00000094916
- UniProt
- P45973
- Genevisible
- P45973
- RefSeq
- NM_001127321
- Aliases
- HEL25; HP1; HP1-ALPHA; HP1A; HP1Hs-alpha
Datasets Table for CBX5
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
CBX5 | K-562 | ENCODE | Homo sapiens | ENCSR272JAT | 9,503 | |||
CBX5 | GM12878 | ENCODE | Homo sapiens | ENCSR372GIN | 12,736 | |||
CBX5 | DKO | GEO | Homo sapiens | GSE135580 | 618 | |||
CBX5 | HCT-116 | GEO | Homo sapiens | GSE135580 | 9,424 | |||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |