CBX6

Information CBX6

Description

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (By similarity). Recruitment to chromatin might occur in an H3K27me3-independent fashion (PubMed:22226355, PubMed:16537902). May have a PRC1-independent function in embryonic stem cells (PubMed:22226355). {ECO:0000250|UniProtKB:O95503, ECO:0000269|PubMed:16537902, ECO:0000269|PubMed:22226355}.(Source UnitProtKB).

Full Name

chromobox 6

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
7,287
Non-redundant peaks
7,287

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
494448
Official Gene Name
Cbx6
JASPAR
MGI
MGI:3512628
Ensembl
ENSMUSG00000089715
UniProt
Q9DBY5
Genevisible
Q9DBY5
RefSeq
NM_028763
Aliases
All peaks CBX6
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Non redundant peaks CBX6
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SEQUENCES CBX6
Download FASTA file
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Datasets Table for CBX6

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CBX6 mESC GEO Mus musculus GSE98723 7,287
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks