CDK8
Information CDK8
- Description
This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
- Full Name
cyclin dependent kinase 8
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 22
- Biotypes
- 10
- Peaks
- 388,822
- Non-redundant peaks
- 204,893
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
Datasets Table for CDK8
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
---|---|---|---|---|---|---|---|---|
CDK8 | MV4-11 | GEO | Homo sapiens | GSE65138 | 5,664 | |||
CDK8 | SET-2 | GEO | Homo sapiens | GSE65138 | 26,973 | |||
CDK8 | monocyte | IFNg | GEO | Homo sapiens | GSE120943 | 8,472 | ||
CDK8 | monocyte | IFNg-LPS | GEO | Homo sapiens | GSE120943 | 9,204 | ||
CDK8 | monocyte | LPS | GEO | Homo sapiens | GSE120943 | 6,375 | ||
CDK8 | monocyte | resting | GEO | Homo sapiens | GSE120943 | 1,256 | ||
CDK8 | MOLM-14 | GEO | Homo sapiens | GSE65138 | 24,685 | |||
CDK8 | MOLM-14 | IBET | GEO | Homo sapiens | GSE65138 | 56,689 | ||
CDK8 | leiomyoma | PT967 | GEO | Homo sapiens | GSE128230 | 14,948 | ||
CDK8 | leiomyoma | PT916 | GEO | Homo sapiens | GSE128230 | 5,985 | ||
CDK8 | leiomyoma | PT1063 | GEO | Homo sapiens | GSE128230 | 7,114 | ||
CDK8 | leiomyoma | PT886 | GEO | Homo sapiens | GSE128230 | 67,017 | ||
CDK8 | leiomyoma | PT848 | GEO | Homo sapiens | GSE128230 | 11,773 | ||
CDK8 | K-562 | GEO | Homo sapiens | GSE65138 | 2,111 | |||
CDK8 | SW480 | GEO | Homo sapiens | GSE53602 | 12,706 | |||
CDK8 | myometrium | PT1063 | GEO | Homo sapiens | GSE128230 | 22,592 | ||
CDK8 | myometrium | PT916 | GEO | Homo sapiens | GSE128230 | 28,064 | ||
CDK8 | myometrium | PT848 | GEO | Homo sapiens | GSE128230 | 10,789 | ||
CDK8 | myometrium | PT886 | GEO | Homo sapiens | GSE128230 | 24,590 | ||
CDK8 | myometrium | PT967 | GEO | Homo sapiens | GSE128230 | 15,274 | ||
CDK8 | MM1-S | GEO | Homo sapiens | GSE43743 | 3,760 | |||
CDK8 | HCT-116 | NOMO | GEO | Homo sapiens | GSE38258 | 22,781 | ||
Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |