CDK9

Information CDK9

Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

Full Name

cyclin dependent kinase 9

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
32
Biotypes
10
Peaks
349,145
Non-redundant peaks
167,727

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
1025
Official Gene Name
CDK9
JASPAR
Ensembl
ENSG00000136807
UniProt
P50750
Genevisible
P50750
RefSeq
NM_001261
Aliases
C-2k; CDC2L4; CTK1; PITALRE; TAK
All peaks CDK9
Download BED file
Non redundant peaks CDK9
Download BED file
SEQUENCES CDK9
Download FASTA file
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Datasets Table for CDK9

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CDK9 A-375 A771726 GEO Homo sapiens GSE57431 4,761
CDK9 A-375 DMSO GEO Homo sapiens GSE68052 7,059
CDK9 A-375 A771726 GEO Homo sapiens GSE68052 4,129
CDK9 A-375 DMSO GEO Homo sapiens GSE57431 9,996
CDK9 A-375 1726 GEO Homo sapiens GSE128080 573
CDK9 A-375 GEO Homo sapiens GSE128080 3,342
CDK9 A-375 1726plus GEO Homo sapiens GSE128080 3,053
CDK9 MV4-11 DMSO GEO Homo sapiens GSE82116 36,359
CDK9 MOLT-4 JQ1 GEO Homo sapiens GSE79288 19,106
CDK9 MOLT-4 DMSO GEO Homo sapiens GSE79288 21,575
CDK9 HEK293T SIJMJD6 GEO Homo sapiens GSE51633 2,556
CDK9 HEK293T SICTR GEO Homo sapiens GSE51633 15,607
CDK9 HEK293T SIBRD4 GEO Homo sapiens GSE51633 7,697
CDK9 BT-474 INHHDAC ENA Homo sapiens ERP010664 5,526
CDK9 BT-474 ENA Homo sapiens ERP010664 5,544
CDK9 Kelly CYC065 GEO Homo sapiens GSE107126 4,418
CDK9 Kelly DMSO GEO Homo sapiens GSE107126 3,457
CDK9 CD4 Th1_BAY GEO Homo sapiens GSE62482 127
CDK9 CD4 Th1_DMSO GEO Homo sapiens GSE62482 155
CDK9 P493-6 CMYC_1H GEO Homo sapiens GSE36354 1,432
CDK9 P493-6 GEO Homo sapiens GSE36354 7,518
CDK9 P493-6 CMYC_24H GEO Homo sapiens GSE36354 251
CDK9 MM1-S JQ1 GEO Homo sapiens GSE42161 111
CDK9 MM1-S JQ1_500NM GEO Homo sapiens GSE42355 42,835
CDK9 MM1-S JQ1_5000NM GEO Homo sapiens GSE49224 34,863
CDK9 MM1-S DMSO GEO Homo sapiens GSE42355 6,939
CDK9 MM1-S DMSO GEO Homo sapiens GSE42161 35,580
CDK9 MM1-S JQ1_50NM GEO Homo sapiens GSE49224 28,640
CDK9 HCT-116 GEO Homo sapiens GSE72622 29,629
CDK9 HCT-116 SHCTR GEO Homo sapiens GSE70408 115
CDK9 HCT-116 KAP1-KO GEO Homo sapiens GSE132705 4,366
CDK9 HCT-116 GEO Homo sapiens GSE132705 1,826
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks