CEBPA

Information CEBPA

Description

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. The use of alternative in-frame non-AUG (CUG) and AUG start codons results in several protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the CUG and the first AUG start codons. [provided by RefSeq, Sep 2014]

Full Name

CCAAT/enhancer binding protein (C/EBP), alpha

Source UniprotKB

Species

Mus musculus [tax_id: 10090]

Genome

mm10

ReMap Statistics

Datasets
53
Biotypes
18
Peaks
1,637,100
Non-redundant peaks
400,320

TF Classification

Familly
Basic leucine zipper factors (bZIP)
Sub Familly
C/EBP-related factors

Source JASPAR

External IDs

NCBI Gene
12606
Official Gene Name
Cebpa
JASPAR
MA0102.2
MGI
MGI:99480
Ensembl
ENSMUSG00000034957
UniProt
P53566
Genevisible
P53566
RefSeq
NM_007678
Aliases
C/EBP alpha; C/ebpalpha; CBF-A; Cebp
All peaks CEBPA
Download BED file
Non redundant peaks CEBPA
Download BED file
SEQUENCES CEBPA
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for CEBPA

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CEBPA liver TCPOBOP-3h GEO Mus musculus GSE121915 77,863
CEBPA pre-B-cell 1h GEO Mus musculus GSE53362 31,984
CEBPA pre-B-cell 30min GEO Mus musculus GSE53362 22,784
CEBPA pre-B-cell 3h GEO Mus musculus GSE53362 24,860
CEBPA pre-B-cell 12h GEO Mus musculus GSE53362 10,803
CEBPA pre-B-cell 10min GEO Mus musculus GSE53362 10,127
CEBPA pre-B-cell 24h GEO Mus musculus GSE53362 8,548
CEBPA macrophage veh GEO Mus musculus GSE111854 7,409
CEBPA macrophage B6_Kdo2-LipidA GEO Mus musculus GSE46494 48,378
CEBPA macrophage KLA-1h GEO Mus musculus GSE111854 10,778
CEBPA macrophage B6 GEO Mus musculus GSE46494 46,291
CEBPA macrophage GEO Mus musculus GSE46494 56,753
CEBPA 3T3 GEO Mus musculus GSE17067 2,215
CEBPA myeloid-progenitor-derived GEO Mus musculus GSE117780 54,416
CEBPA hematopoietic-progenitor GEO Mus musculus GSE84328 64,797
CEBPA hematopoietic-progenitor GEO Mus musculus GSE47003 38,335
CEBPA AML MLL-AF9_LSD1-inhibitor GEO Mus musculus GSE100758 23,139
CEBPA MSC veh_d7 GEO Mus musculus GSE79813 60,741
CEBPA primary-B-cell GEO Mus musculus GSE52373 103
CEBPA primary-B-cell estradiol GEO Mus musculus GSE52373 1,371
CEBPA B-cell CEBPA-18h GEO Mus musculus GSE71215 12,681
CEBPA brown-adipocyte d6 GEO Mus musculus GSE83757 9,632
CEBPA brown-adipocyte d0 GEO Mus musculus GSE83757 2,793
CEBPA brown-preadipocyte D7 GEO Mus musculus GSE74189 30,712
CEBPA 3T3-L1 GEO Mus musculus GSE56745 11,850
CEBPA bone-marrow leukemia_300pg GEO Mus musculus GSE55850 70,634
CEBPA bone-marrow inactivation GEO Mus musculus GSE103446 33,919
CEBPA bone-marrow HMM GEO Mus musculus GSE103446 31,894
CEBPA bone-marrow gmpG GEO Mus musculus GSE89767 37,064
CEBPA bone-marrow leukemia_10K GEO Mus musculus GSE55850 39,370
CEBPA bone-marrow leukemia_50pg GEO Mus musculus GSE55850 38,823
CEBPA BV-2 Nmu GEO Mus musculus GSE54443 3,884
CEBPA BV-2 Nwt GEO Mus musculus GSE54443 17,564
CEBPA myeloid-progenitor-derived DMSO GEO Mus musculus GSE117780 26,889
CEBPA MLL-AF9 GEO Mus musculus GSE120063 77,357
CEBPA bone-marrow Mx-cre GEO Mus musculus GSE118963 70,648
CEBPA bone-marrow GEO Mus musculus GSE103446 35,975
CEBPA bone-marrow gmpM GEO Mus musculus GSE89767 18,679
CEBPA bone-marrow leukemia_100pg GEO Mus musculus GSE55850 76,206
CEBPA pre-B-cell 48h GEO Mus musculus GSE53362 7,309
CEBPA macrophage Kdo2-LipidA GEO Mus musculus GSE46494 50,537
CEBPA macrophage KLA-1h GEO Mus musculus GSE48759 48,384
CEBPA macrophage GEO Mus musculus GSE48759 14,579
CEBPA MEF 48h GEO Mus musculus GSE90893 50,027
CEBPA MEF GEO Mus musculus GSE90893 47,852
CEBPA hematopoietic-progenitor GEO Mus musculus GSE58361 22,340
CEBPA liver HFD GEO Mus musculus GSE124463 43,989
CEBPA liver GEO Mus musculus GSE17067 13,072
CEBPA liver LFD GEO Mus musculus GSE124463 5,483
CEBPA hematopoietic-stem-cell GEO Mus musculus GSE43007 1,589
CEBPA AML PuER GEO Mus musculus GSE63317 32,420
CEBPA AML EV GEO Mus musculus GSE63317 40,984
CEBPA BV-2 pCDH GEO Mus musculus GSE54443 10,266
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks