CHAF1A
Information CHAF1A
- Description
Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. {ECO:0000250|UniProtKB:Q5R1T0}.(Source UnitProtKB).
- Full Name
chromatin assembly factor 1, subunit A (p150)
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 12,025
- Non-redundant peaks
- 12,025
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 27221
- Official Gene Name
- Chaf1a
- JASPAR
- MGI
- MGI:1351331
- Ensembl
- ENSMUSG00000002835
- UniProt
- Q9QWF0
- Genevisible
- Q9QWF0
- RefSeq
- NM_013733
- Aliases
- AL023013; AL024058; CAF-1; Cac1p