CHES-1-like

The gene Checkpoint suppressor 1-like is referred to in FlyBase by the symbol DmelCHES-1-like (CG12690, FBgn0029504). It is a protein_coding_gene from Dmel. It has 4 annotated transcripts and 4 polypeptides (2 unique). Gene sequence location is X:7682338..7709385. Its molecular function is described by: transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of cell division; mitotic G1 DNA damage checkpoint; cellular response to hypoxia; embryonic heart tube development. 43 alleles are reported. The phenotypes of these alleles manifest in: cell; pericardial cell; circulatory system; germline cyst; multi-tissue structure. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; hyperplasia; male semi-fertile; visible; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.

Checkpoint suppressor 1-like

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6