CREM

Information CREM

Description

This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]

Full Name

cAMP responsive element modulator

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
3
Biotypes
3
Peaks
139,102
Non-redundant peaks
112,947

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
1390
Official Gene Name
CREM
JASPAR
Ensembl
ENSG00000095794
UniProt
Q03060
Genevisible
Q03060
RefSeq
NM_001267562
Aliases
CREM-2; ICER; hCREM-2
All peaks CREM
Download BED file
Non redundant peaks CREM
Download BED file
SEQUENCES CREM
Download FASTA file
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Datasets Table for CREM

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CREM K-562 ENCODE Homo sapiens ENCSR077DKV 65,648
CREM Hep-G2 ENCODE Homo sapiens ENCSR903ELW 27,326
CREM GM12878 ENCODE Homo sapiens ENCSR839XZU 46,128
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks