CRX

Information CRX

Description

Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. {ECO:0000269|PubMed:16574740}.(Source UnitProtKB).

Full Name

cone-rod homeobox

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
1
Peaks
73,467
Non-redundant peaks
36,888

TF Classification

Super Class
0
Class
Homeo domain factors
Familly
Paired-related HD factors
Sub Familly
0

Source TFClass

External IDs

NCBI Gene
12951
Official Gene Name
Crx
JASPAR
MA0467.1
Ensembl
ENSMUSG00000041578
UniProt
O54751
Genevisible
O54751
RefSeq
Aliases
Crx1
All peaks CRX
Download BED file
Non redundant peaks CRX
Download BED file
SEQUENCES CRX
Download FASTA file
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Datasets Table for CRX

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CRX retina Nrl-KO GEO Mus musculus GSE20012 4,183
CRX retina GEO Mus musculus GSE20012 6,354
CRX retina Hu3 GEO Mus musculus GSE137311 25,999
CRX retina Hu6 GEO Mus musculus GSE137311 30,858
CRX retina Hu20 GEO Mus musculus GSE137311 13,862
CRX retina Hu21 GEO Mus musculus GSE137311 2,748
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks