CRY1

Information CRY1

Description

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]

Full Name

cryptochrome circadian regulator 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
4
Biotypes
1
Peaks
55,837
Non-redundant peaks
42,140

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
1407
Official Gene Name
CRY1
JASPAR
Ensembl
ENSG00000008405
UniProt
Q16526
Genevisible
Q16526
RefSeq
NM_004075
Aliases
DSPD; PHLL1
All peaks CRY1
Download BED file
Non redundant peaks CRY1
Download BED file
SEQUENCES CRY1
Download FASTA file
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Datasets Table for CRY1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CRY1 U2OS cordycepin GEO Homo sapiens GSE130506 7,478
CRY1 U2OS GEO Homo sapiens GSE130602 12,429
CRY1 U2OS DMSO GEO Homo sapiens GSE130506 12,344
CRY1 U2OS GEO Homo sapiens GSE44236 23,586
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks