CRY2
Information CRY2
- Description
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
- Full Name
cryptochrome circadian regulator 2
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 14,774
- Non-redundant peaks
- 14,182
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 1408
- Official Gene Name
- CRY2
- JASPAR
- Ensembl
- ENSG00000121671
- UniProt
- Q49AN0
- Genevisible
- Q49AN0
- RefSeq
- NM_001127457
- Aliases
- HCRY2; PHLL2
Datasets Table for CRY2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CRY2 | U2OS | GEO | Homo sapiens | GSE130602 | 12,138 | |||
| CRY2 | U2OS | DMSO | GEO | Homo sapiens | GSE130507 | 2,636 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |