DDX5
Information DDX5
- Description
This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017]
- Full Name
DEAD-box helicase 5
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 67,251
- Non-redundant peaks
- 66,340
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 1655
- Official Gene Name
- DDX5
- JASPAR
- Ensembl
- ENSG00000108654
- UniProt
- P17844
- Genevisible
- P17844
- RefSeq
- NM_001320595
- Aliases
- G17P1; HLR1; HUMP68; p68
Datasets Table for DDX5
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| DDX5 | BT-549 | GEO | Homo sapiens | GSE112961 | 13,433 | |||
| DDX5 | NTERA2 | GEO | Homo sapiens | GSE58641 | 52,647 | |||
| DDX5 | HeLa | GEO | Homo sapiens | GSE24126 | 1,171 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |