DNMT1
Information DNMT1
- Description
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
- Full Name
DNA methyltransferase 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 1,627
- Non-redundant peaks
- 1,627
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 1786
- Official Gene Name
- DNMT1
- JASPAR
- Ensembl
- ENSG00000130816
- UniProt
- P26358
- Genevisible
- P26358
- RefSeq
- NM_001130823
- Aliases
- ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI
Datasets Table for DNMT1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| DNMT1 | K-562 | ENCODE | Homo sapiens | ENCSR987PBI | 1,627 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |