DNMT3B
Information DNMT3B
- Description
This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]
- Full Name
DNA methyltransferase 3B
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 6
- Biotypes
- 2
- Peaks
- 59,152
- Non-redundant peaks
- 58,815
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 13436
- Official Gene Name
- Dnmt3b
- JASPAR
- MGI
- MGI:1261819
- Ensembl
- ENSMUSG00000027478
- UniProt
- O88509
- Genevisible
- O88509
- RefSeq
- NM_010068
- Aliases
- MmuIIIB
Datasets Table for DNMT3B
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| DNMT3B | mESC | ShCtr | GEO | Mus musculus | GSE72853 | 2,279 | ||
| DNMT3B | mESC | mock | GEO | Mus musculus | GSE72853 | 131 | ||
| DNMT3B | mESC | Dnmt3b-mut | GEO | Mus musculus | GSE72853 | 1,513 | ||
| DNMT3B | mESC | GEO | Mus musculus | GSE57412 | 49,985 | |||
| DNMT3B | EPC | ganglionic-gut_9 | GEO | Mus musculus | GSE92942 | 1,542 | ||
| DNMT3B | mESC | ShSetd2 | GEO | Mus musculus | GSE72853 | 3,702 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |