Dref

The gene DNA replication-related element factor is referred to in FlyBase by the symbol DmelDref (CG5838, FBgn0015664). It is a protein_coding_gene from Dmel. It has 2 annotated transcripts and 2 polypeptides (1 unique). Gene sequence location is 2L:9964147..9967229. Its molecular function is described by: RNA polymerase II core promoter sequence-specific DNA binding; calcium ion binding; DNA binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with 15 unique terms, many of which group under: chaeta development; dendrite morphogenesis; programmed cell death; sensory organ precursor cell division; DNA-dependent DNA replication. 24 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; organelle; wing sensillum; stem cell; acellular anatomical structure. The phenotypic classes of alleles include: increased mortality; cell death defective; mitotic cell cycle defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

DNA replication-related element factor

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6