E-bx

The gene Enhancer of bithorax is referred to in FlyBase by the symbol DmelE(bx) (CG32346, FBgn0000541). It is a protein_coding_gene from Dmel. It has 9 annotated transcripts and 9 polypeptides (7 unique). Gene sequence location is 3L:233926..246912. Its molecular function is described by: methylated histone binding; lysine-acetylated histone binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; nuclear receptor binding. It is involved in the biological process described with 12 unique terms, many of which group under: cellular component organization or biogenesis; multicellular organismal process; intracellular steroid hormone receptor signaling pathway; regulation of response to external stimulus; reproduction. 33 alleles are reported. The phenotypes of these alleles manifest in: cellular anatomical entity; intracellular non-membrane-bounded organelle; intracellular organelle; embryonic/larval fat body; non-connected functional system. The phenotypic classes of alleles include: increased mortality during development; increased mortality; size defective; phenotype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Enhancer of bithorax

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6