E-spl-m-beta-HLH

The gene Enhancer of split mbeta, helix-loop-helix is referred to in FlyBase by the symbol DmelE(spl)mbeta-HLH (CG14548, FBgn0002733). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26005046..26006023. Its molecular function is described by 6 unique terms, many of which group under: sequence-specific DNA binding; double-stranded DNA binding; binding; transcription regulator activity; heterocyclic compound binding. It is involved in the biological process described with 6 unique terms, many of which group under: neuroblast proliferation; negative regulation of biosynthetic process; neural precursor cell proliferation; pattern specification process; positive regulation of cell development. 18 alleles are reported. The phenotypes of these alleles manifest in: chaeta; multicellular structure; organ system subdivision; mesothoracic bristle; dorsal mesothorax. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; some die during pupal stage; fertile; visible; viable. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages, during early pupal stages.

Enhancer of split mbeta, helix-loop-helix

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6