E-spl-m3-HLH

The gene Enhancer of split m3, helix-loop-helix is referred to in FlyBase by the symbol DmelE(spl)m3-HLH (CG8346, FBgn0002609). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26021823..26023127. Its molecular function is described by: RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding; protein dimerization activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; anterior/posterior pattern specification; regulation of neurogenesis; positive regulation of neuroblast proliferation. 14 alleles are reported. The phenotypes of these alleles manifest in: wing; scutellar bristle. The phenotypic classes of alleles include: lethal - all die before end of pupal stage; visible; some die during pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages.

Enhancer of split m3, helix-loop-helix

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6