E-spl-m7-HLH

The gene Enhancer of split m7, helix-loop-helix is referred to in FlyBase by the symbol DmelE(spl)m7-HLH (CG8361, FBgn0002633). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26037038..26038019. Its molecular function is described by 7 unique terms, many of which group under: binding; sequence-specific DNA binding; double-stranded DNA binding; heterocyclic compound binding; protein binding. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; regulation of neurogenesis; anterior/posterior pattern specification. 34 alleles are reported. The phenotypes of these alleles manifest in: proneural cluster; neuron projection bundle; larval thoracic neuromere; interommatidial bristle; larval segment. The phenotypic classes of alleles include: phenotype; visible; increased mortality; lethal - all die before end of pupal stage. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 06-12 hour embryonic stages.

Enhancer of split m7, helix-loop-helix

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6