E-spl-m8-HLH

The gene Enhancer of split m8, helix-loop-helix is referred to in FlyBase by the symbol DmelE(spl)m8-HLH (CG8365, FBgn0000591). It is a protein_coding_gene from Dmel. It has one annotated transcript and one polypeptide. Gene sequence location is 3R:26040240..26041008. Its molecular function is described by 6 unique terms, many of which group under: DNA-binding transcription factor activity, RNA polymerase II-specific; binding; DNA-binding transcription factor activity; organic cyclic compound binding; protein binding. It is involved in the biological process described with 8 unique terms, many of which group under: developmental process; regulation of metabolic process; anatomical structure development; sensory organ development; pattern specification process. 105 alleles are reported. The phenotypes of these alleles manifest in: abdominal ventral multidendritic neuron; anterior fascicle sensory neuron; trunk mesoderm derivative; embryonic epidermis; ventral triple row bristle. The phenotypic classes of alleles include: phenotype; increased mortality; cell number defective; increased mortality during development. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed within 06-12 hour embryonic stages.

Enhancer of split m8, helix-loop-helix

Source FlyBase

Drosophila melanogaster [tax_id: 7227]

dm6