E-z

Information E-z

Description

The gene Enhancer of zeste is referred to in FlyBase by the symbol DmelE(z) (CG6502, FBgn0000629). It is a protein_coding_gene from Dmel. It has 3 annotated transcripts and 3 polypeptides (2 unique). Gene sequence location is 3L:10634575..10638130. Its molecular function is described by 6 unique terms, many of which group under: binding; DNA binding; nucleic acid binding; histone methyltransferase activity; catalytic activity, acting on a protein. It is involved in the biological process described with 11 unique terms, many of which group under: cellular developmental process; RNA biosynthetic process; neuron development; syncytial blastoderm mitotic cell cycle; neuroblast proliferation. 125 alleles are reported. The phenotypes of these alleles manifest in: head; oocyte nucleus; abdominal segment 9; genital disc; plasma membrane bounded cell projection. The phenotypic classes of alleles include: visible; phenotype; modifier of variegation; increased mortality. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Full Name

Enhancer of zeste

Source FlyBase

Species

Drosophila melanogaster [tax_id: 7227]

Genome

dm6

ReMap Statistics

Datasets
9
Biotypes
4
Peaks
101,284
Non-redundant peaks
50,866

TF Classification

Familly
NA
Sub Familly
NA

Source JASPAR

External IDs

NCBI Gene
39203
Official Gene Name
E(z)
JASPAR
Ensembl
FBgn0000629
UniProt
P42124
Genevisible
P42124
RefSeq
NM_079297
Aliases
E(z)
All peaks E-z
Download BED file
Non redundant peaks E-z
Download BED file
SEQUENCES E-z
Download FASTA file
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Datasets Table for E-z

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
E-z adult whole-fly_site-specific-recombination_insertion ENCODE Drosophila melanogaster ENCSR032HMJ 22,400
E-z embryo 0h-16h_rev GEO Drosophila melanogaster GSE59192 693
E-z embryo 12h-24h GEO Drosophila melanogaster GSE66183 6,501
E-z S2-DRSC abd-A-HA_SC-dN-20 GEO Drosophila melanogaster GSE101554 15,345
E-z S2-DRSC SC-dN-20 GEO Drosophila melanogaster GSE101554 16,312
E-z third-instar imaginal-discs-and-brains GEO Drosophila melanogaster GSE102339 7,638
E-z third-instar Spps-KO_imaginal-discs-and-brains GEO Drosophila melanogaster GSE102339 3,600
E-z third-instar GEO Drosophila melanogaster GSE65566 14,239
E-z third-instar psc-min GEO Drosophila melanogaster GSE65566 14,556
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks