E2F3
Information E2F3
- Description
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000269|PubMed:20176812}.(Source UnitProtKB).
- Full Name
E2F transcription factor 3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 4
- Biotypes
- 1
- Peaks
- 10,232
- Non-redundant peaks
- 8,413
TF Classification
- Familly
- Fork head / winged helix factors
- Sub Familly
- E2F-related factors
Source JASPAR
External IDs
- NCBI Gene
- 13557
- Official Gene Name
- E2f3
- JASPAR
- MA0469.1
- MGI
- MGI:1096340
- Ensembl
- ENSMUSG00000016477
- UniProt
- O35261
- Genevisible
- O35261
- RefSeq
- NM_010093
- Aliases
- E2F3b; E2f3a
Datasets Table for E2F3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| E2F3 | MEF | GEO | Mus musculus | GSE71376 | 3,484 | |||
| E2F3 | MEF | KO | GEO | Mus musculus | GSE33791 | 916 | ||
| E2F3 | MEF | GEO | Mus musculus | GSE33791 | 5,539 | |||
| E2F3 | MEF | KO | GEO | Mus musculus | GSE71376 | 293 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |