E2F3

Information E2F3

Description

This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Full Name

E2F transcription factor 3

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
11,749
Non-redundant peaks
11,749

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

NCBI Gene
1871
Official Gene Name
E2F3
JASPAR
MA0469
Ensembl
ENSG00000112242
UniProt
O00716
Genevisible
O00716
RefSeq
NM_001243076
Aliases
E2F-3
All peaks E2F3
Download BED file
Non redundant peaks E2F3
Download BED file
SEQUENCES E2F3
Download FASTA file
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Datasets Table for E2F3

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
E2F3 K-562 ENCODE Homo sapiens ENCSR036QIR 11,749
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks