E4F1
Information E4F1
- Description
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]
- Full Name
E4F transcription factor 1
Source NCBI
- Species
Homo sapiens [tax_id: 9606]
- Genome
hg38
ReMap Statistics
- Datasets
- 3
- Biotypes
- 3
- Peaks
- 66,104
- Non-redundant peaks
- 58,420
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- NCBI Gene
- 1877
- Official Gene Name
- E4F1
- JASPAR
- Ensembl
- ENSG00000167967
- UniProt
- Q66K89
- Genevisible
- Q66K89
- RefSeq
- NM_001288776
- Aliases
- E4F
Datasets Table for E4F1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| E4F1 | MCF-7 | ENCODE | Homo sapiens | ENCSR841YWU | 4,810 | |||
| E4F1 | K-562 | ENCODE | Homo sapiens | ENCSR731LHZ | 41,654 | |||
| E4F1 | GM12878 | ENCODE | Homo sapiens | ENCSR439WAF | 19,640 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |