EBF2
Information EBF2
- Description
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. {ECO:0000269|PubMed:16326388}.(Source UnitProtKB).
- Full Name
early B cell factor 2
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 5
- Biotypes
- 3
- Peaks
- 108,451
- Non-redundant peaks
- 73,699
TF Classification
- Familly
- Rel homology region (RHR) factors
- Sub Familly
- Early B-Cell Factor-related factors
Source JASPAR
External IDs
- NCBI Gene
- 13592
- Official Gene Name
- Ebf2
- JASPAR
- MA1604.1
- MGI
- MGI:894332
- Ensembl
- ENSMUSG00000022053
- UniProt
- O08792
- Genevisible
- O08792
- RefSeq
- NM_010095
- Aliases
- D14Ggc1e; EBF-2; Mmot1; O/E-3; OE-3
Datasets Table for EBF2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| EBF2 | brown-adipocyte | d6 | GEO | Mus musculus | GSE83757 | 8,789 | ||
| EBF2 | brown-adipose-tissue | GEO | Mus musculus | GSE97114 | 42,532 | |||
| EBF2 | brown-preadipocyte | D7 | GEO | Mus musculus | GSE74189 | 14,620 | ||
| EBF2 | brown-preadipocyte | D0 | GEO | Mus musculus | GSE74189 | 35,885 | ||
| EBF2 | brown-preadipocyte | D3 | GEO | Mus musculus | GSE74189 | 6,625 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |