EGR1

Information EGR1

Description

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]

Full Name

early growth response 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
26
Biotypes
15
Peaks
435,148
Non-redundant peaks
192,833

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
C2H2 zinc finger factors
Familly
Three-zinc finger Krüppel-related factors
Sub Familly
EGR factors

Source TFClass

External IDs

NCBI Gene
1958
Official Gene Name
EGR1
JASPAR
MA0162
Ensembl
ENSG00000120738
UniProt
P18146
Genevisible
P18146
RefSeq
NM_001964
Aliases
AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225
All peaks EGR1
Download BED file
Non redundant peaks EGR1
Download BED file
SEQUENCES EGR1
Download FASTA file
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Datasets Table for EGR1

Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
EGR1 macrophage D4 GEO Homo sapiens GSE136216 14,432
EGR1 macrophage D1 GEO Homo sapiens GSE136216 3,390
EGR1 macrophage D2 GEO Homo sapiens GSE136216 130
EGR1 macrophage D3 GEO Homo sapiens GSE136216 12,631
EGR1 A2780 GEO Homo sapiens GSE129700 2,433
EGR1 A2780 cisplatin GEO Homo sapiens GSE129700 5,438
EGR1 A-375 GEO Homo sapiens GSE116190 23,346
EGR1 monocyte GEO Homo sapiens GSE136216 454
EGR1 HL-60 PMA GEO Homo sapiens GSE106359 7,062
EGR1 HL-60 GEO Homo sapiens GSE106359 5,442
Target nameTarget modificationEcotype/StrainBiotypeBiotype modificationSourceSpeciesExperimentPeaks
Showing 1 to 10 of 26 entries