EGR1

Information EGR1

Description

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]

Full Name

early growth response 1

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
26
Biotypes
15
Peaks
435,148
Non-redundant peaks
192,833

TF Classification

Super Class
Zinc-coordinating DNA-binding domains
Class
C2H2 zinc finger factors
Familly
Three-zinc finger Krüppel-related factors
Sub Familly
EGR factors

Source TFClass

External IDs

NCBI Gene
1958
Official Gene Name
EGR1
JASPAR
MA0162
Ensembl
ENSG00000120738
UniProt
P18146
Genevisible
P18146
RefSeq
NM_001964
Aliases
AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225

External links
All peaks EGR1
Download BED file
Non redundant peaks EGR1
Download BED file
SEQUENCES EGR1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for EGR1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
EGR1 macrophage D4 GEO Homo sapiens GSE136216 14,432
EGR1 macrophage D1 GEO Homo sapiens GSE136216 3,390
EGR1 macrophage D2 GEO Homo sapiens GSE136216 130
EGR1 macrophage D3 GEO Homo sapiens GSE136216 12,631
EGR1 A2780 GEO Homo sapiens GSE129700 2,433
EGR1 A2780 cisplatin GEO Homo sapiens GSE129700 5,438
EGR1 A-375 GEO Homo sapiens GSE116190 23,346
EGR1 monocyte GEO Homo sapiens GSE136216 454
EGR1 HL-60 PMA GEO Homo sapiens GSE106359 7,062
EGR1 HL-60 GEO Homo sapiens GSE106359 5,442
EGR1 Hep-G2 ENCODE Homo sapiens ENCSR026GSW 75,278
EGR1 WA01 ENCODE Homo sapiens ENCSR000BJA 9,407
EGR1 MCF-7 ENCODE Homo sapiens ENCSR000BUX 10,633
EGR1 K-562 ENCODE Homo sapiens ENCSR000BNE 45,761
EGR1 K-562 ENCODE Homo sapiens ENCSR024CNP 29,280
EGR1 K-562 ENCODE Homo sapiens ENCSR211LTF 29,443
EGR1 liver ENCODE Homo sapiens ENCSR290ZOS 7,845
EGR1 liver ENCODE Homo sapiens ENCSR736BUG 20,149
EGR1 Ishikawa ENCODE Homo sapiens ENCSR000BSQ 14,334
EGR1 GM12878 ENCODE Homo sapiens ENCSR000BMQ 23,084
EGR1 GM12878 ENCODE Homo sapiens ENCSR000BRG 2,128
EGR1 fibroblast DOX-CLOB-24h GEO Homo sapiens GSE134924 25,260
EGR1 fibroblast DOX-24h GEO Homo sapiens GSE134924 29,605
EGR1 fibroblast EtOH-24h GEO Homo sapiens GSE134924 8,942
EGR1 HCT-116 ENCODE Homo sapiens ENCSR000BRZ 10,812
EGR1 T-HESCs GEO Homo sapiens GSE141063 18,429
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks