ESRRA
Information ESRRA
- Description
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle (By similarity). {ECO:0000250}.(Source UnitProtKB).
- Full Name
estrogen related receptor, alpha
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 128,357
- Non-redundant peaks
- 87,602
TF Classification
- Familly
- Nuclear receptors with C4 zinc fingers
- Sub Familly
- Steroid hormone receptors (NR3)
Source JASPAR
External IDs
- NCBI Gene
- 26379
- Official Gene Name
- Esrra
- JASPAR
- MA0592.2
- MGI
- MGI:1346831
- Ensembl
- ENSMUSG00000024955
- UniProt
- O08580
- Genevisible
- O08580
- RefSeq
- NM_007953
- Aliases
- ERRalpha; Err1; Estrra; Nr3b1
Datasets Table for ESRRA
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ESRRA | liver | GEO | Mus musculus | GSE43638 | 29,664 | |||
| ESRRA | BAT | adiponectin | GEO | Mus musculus | GSE83926 | 51,282 | ||
| ESRRA | BAT | GEO | Mus musculus | GSE83926 | 47,411 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |