ETV6

Information ETV6

Description

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]

Full Name

ETS variant transcription factor 6

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
6
Biotypes
3
Peaks
79,954
Non-redundant peaks
53,729

TF Classification

Super Class
Helix-turn-helix domains
Class
Tryptophan cluster factors
Familly
Ets-related factors
Sub Familly
ETV6-like factors

Source TFClass

External IDs

NCBI Gene
2120
Official Gene Name
ETV6
JASPAR
MA0645
Ensembl
ENSG00000139083
UniProt
P41212
Genevisible
P41212
RefSeq
NM_001987
Aliases
TEL; TEL/ABL; THC5
All peaks ETV6
Download BED file
Non redundant peaks ETV6
Download BED file
SEQUENCES ETV6
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for ETV6

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ETV6 Reh pCCL-ETV6-HA GEO Homo sapiens GSE102785 7,329
ETV6 GM12878 GEO Homo sapiens GSE97661 29,806
ETV6 K-562 ENCODE Homo sapiens ENCSR124BJR 6,720
ETV6 K-562 ENCODE Homo sapiens ENCSR000FCE 4,565
ETV6 GM12878 ENCODE Homo sapiens ENCSR597VGC 4,863
ETV6 GM12878 ENCODE Homo sapiens ENCSR626VUC 26,671
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks