FLI1

Information FLI1

Description

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Full Name

Fli-1 proto-oncogene, ETS transcription factor

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
30
Biotypes
10
Peaks
569,967
Non-redundant peaks
226,598

TF Classification

Super Class
Helix-turn-helix domains
Class
Tryptophan cluster factors
Familly
Ets-related factors
Sub Familly
Ets-like factors

Source TFClass

External IDs

NCBI Gene
2313
Official Gene Name
FLI1
JASPAR
MA0475
Ensembl
ENSG00000151702
UniProt
Q01543
Genevisible
Q01543
RefSeq
NM_001167681
Aliases
BDPLT21; EWSR2; SIC-1
All peaks FLI1
Download BED file
Non redundant peaks FLI1
Download BED file
SEQUENCES FLI1
Download FASTA file
DOWNLOAD All ReMap
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Datasets Table for FLI1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FLI1 TSU-1621MT GEO Homo sapiens GSE60477 28,326
FLI1 SKNO-1 GEO Homo sapiens GSE23730 56,456
FLI1 UAE GEO Homo sapiens GSE23730 27,381
FLI1 UAE ZINC GEO Homo sapiens GSE23730 31,801
FLI1 ME-1 GEO Homo sapiens GSE46044 12,366
FLI1 SK-N-MC SHFLI_96H GEO Homo sapiens GSE61944 301
FLI1 SK-N-MC SHGFP_96H GEO Homo sapiens GSE61944 4,036
FLI1 SK-N-MC SHFLI_48H GEO Homo sapiens GSE61944 716
FLI1 SK-N-MC GEO Homo sapiens GSE61944 3,020
FLI1 SK-N-MC SHGFP_48H GEO Homo sapiens GSE61944 4,299
FLI1 SEM GEO Homo sapiens GSE117864 34,622
FLI1 NB4 GEO Homo sapiens GSE23730 17,464
FLI1 HUVEC-C GEO Homo sapiens GSE109625 370
FLI1 HUVEC-C VEGF_12h GEO Homo sapiens GSE109625 5,750
FLI1 HUVEC-C VEGF_1h GEO Homo sapiens GSE109625 4,289
FLI1 HUVEC-C VEGF_4h GEO Homo sapiens GSE109625 1,174
FLI1 HUVEC-C GEO Homo sapiens GSE109695 57,647
FLI1 CTV-1 DSG GEO Homo sapiens GSE128835 28,037
FLI1 CTV-1 DSG_SPI1-mut GEO Homo sapiens GSE128835 22,417
FLI1 A-673 D11 GEO Homo sapiens GSE129155 22,144
FLI1 A-673 D10 GEO Homo sapiens GSE129155 2,131
FLI1 A-673 D14 GEO Homo sapiens GSE129155 24,740
FLI1 A-673 D7 GEO Homo sapiens GSE129155 7,269
FLI1 A-673 D9 GEO Homo sapiens GSE129155 1,577
FLI1 A-673 D17 GEO Homo sapiens GSE129155 28,501
FLI1 A-673 2_KRAB_eSOX2_1 GEO Homo sapiens GSE106914 52,559
FLI1 A-673 1_KRAB_GFP GEO Homo sapiens GSE106914 71,463
FLI1 A-673 delta22_EWSFL-kd GEO Homo sapiens GSE94480 125
FLI1 A-673 Mut9_EWSFL-kd GEO Homo sapiens GSE94480 908
FLI1 A-673 GEO Homo sapiens GSE99959 18,078
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks