FOSL2

Information FOSL2

Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014]

Full Name

FOS like 2, AP-1 transcription factor subunit

Source NCBI

Species

Homo sapiens [tax_id: 9606]

Genome

hg38

ReMap Statistics

Datasets
15
Biotypes
9
Peaks
468,451
Non-redundant peaks
189,341

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
Fos-related factors
Sub Familly
Fos factors

Source TFClass

External IDs

NCBI Gene
2355
Official Gene Name
FOSL2
JASPAR
MA1145
Ensembl
ENSG00000075426
UniProt
P15408
Genevisible
P15408
RefSeq
NM_005253
Aliases
FLJ23306; FRA2
All peaks FOSL2
Download BED file
Non redundant peaks FOSL2
Download BED file
SEQUENCES FOSL2
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for FOSL2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FOSL2 LPS141 GEO Homo sapiens GSE111253 38,702
FOSL2 MCF-7 abemaciclib GEO Homo sapiens GSE157216 3,053
FOSL2 MCF-7 DMSO GEO Homo sapiens GSE157216 975
FOSL2 HFOB DIFF GEO Homo sapiens GSE82295 2,103
FOSL2 A-549 ENCODE Homo sapiens ENCSR448TVS 51,105
FOSL2 MDA-MB-231 GEO Homo sapiens GSE132098 10,171
FOSL2 SK-N-SH ENCODE Homo sapiens ENCSR000BVB 56,044
FOSL2 MCF-7 ENCODE Homo sapiens ENCSR546KCN 11,923
FOSL2 MCF-7 ENCODE Homo sapiens ENCSR000BUI 28,306
FOSL2 Hep-G2 ENCODE Homo sapiens ENCSR000BHP 42,418
FOSL2 A-549 ENCODE Homo sapiens ENCSR000BQO 57,909
FOSL2 hESC GEO Homo sapiens GSE69539 42,662
FOSL2 NPC GEO Homo sapiens GSE122631 5,513
FOSL2 NPC R1159Q GEO Homo sapiens GSE122631 59,281
FOSL2 NPC K755R-pos GEO Homo sapiens GSE122631 58,286
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks