FOXA3
Information FOXA3
- Description
Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; activates GLUT2 transcription. Involved in regulation of neuronal-specific transcription. Involved in regulation of spermatogenesis; required for the maintenance of the testicular germ cell population and male fertility. {ECO:0000250, ECO:0000269|PubMed:11546810, ECO:0000269|PubMed:17488644, ECO:0000269|PubMed:9632808}.(Source UnitProtKB).
- Full Name
forkhead box A3
Source UniprotKB
- Species
Mus musculus [tax_id: 10090]
- Genome
mm10
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 8,971
- Non-redundant peaks
- 7,318
TF Classification
- Familly
- NA
- Sub Familly
- NA
Source JASPAR
External IDs
- NCBI Gene
- 15377
- Official Gene Name
- Foxa3
- JASPAR
- MGI
- MGI:1347477
- Ensembl
- ENSMUSG00000040891
- UniProt
- P35584
- Genevisible
- P35584
- RefSeq
- Aliases
- Hnf-3g; Hnf3g; Tcf-3g; Tcf3g
Datasets Table for FOXA3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| FOXA3 | liver | FoxAflox_Alfp-Cre | GEO | Mus musculus | GSE77670 | 5,139 | ||
| FOXA3 | liver | GEO | Mus musculus | GSE77670 | 3,832 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |